Intravenous rAAV2/9 injection for murine cochlear gene delivery

Oxytocin injection after caesarean delivery: intravenous or intramyometrial?

PURPOSE To determine, after Caesarean delivery, uterine contractility and blood pressure following intravenous (i.v.) and intramyometrial (imy) injection of oxytocin. METHODS In a double-blind clinical trial 40 parturients scheduled for elective Caesarean section with spinal anaesthesia were randomized into two equal groups. One litre Ringer's lactate was administered i.v. before intrathecal ...

Effective in vitro gene delivery to murine cancerous brain cells using carbon nanotube-polyethylenimine conjugates

Objective(s): Carbon nanotube (CNT) has been widely applied at molecular and cellular levels due to its exceptional properties. Studies based on conjugation of CNTs with biological molecules indicated that biological activity is preserved. Polyethylenimine (PEI) is explored in designing novel gene delivery vectors due to its ability to condense plasmid DNA through electrostatic attraction. In t...

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

Widespread gene transfer to the retina is challenging as it requires vector systems to overcome physical and biochemical barriers to enter and diffuse throughout retinal tissue. We investigated whether exosome-associated adeno-associated virus, (exo-AAV) enabled broad retinal targeting following intravitreal (IVT) injection, as exosomes have been shown to traverse biological barriers and mediat...

Oxaliplatin injection for intravenous use

————————————— DOSAGE AND ADMINISTRATION ————————————— • Administer oxaliplatin in combination with 5-fluorouracil/leucovorin every 2 weeks. (2.1): – Day 1: Oxaliplatin 85 mg/m intravenous infusion in 250–500 mL 5% Dextrose Injection, USP and leucovorin 200 mg/m intravenous infusion in 5% Dextrose Injection, USP both given over 120 minutes at the same time in separate bags using a Y-line, follow...

Delivery systems for intravenous nitroglycerin.